Datasets:
surrey-nlp
/
PLOD-filtered

Dataset card Viewer Files Community
1
id
stringlengths
1
6
tokens
sequence
pos_tags
sequence
ner_tags
sequence
100
[ "To", "expand", "on", "this", "knowledge", ",", "we", "performed", "differential", "expression", "analysis", "of", "RNA", "sequencing", "data", "from", "a", "variety", "of", "sources", "of", "cholangiocytes", ":", "1", ")", "iDC", ";", "2", ")", "the", "NHC", "cell", "line", ";", "and", "3", ")", "isolated", "human", "cholangiocytes", "(", "IHC", ")", ".", "We", "compared", "the", "data", "from", "these", "various", "cholangiocytes", "to", "publicly", "available", "hepatocyte", "sequencing", "data", "." ]
[ 10, 16, 1, 6, 8, 13, 11, 16, 0, 8, 8, 1, 8, 8, 8, 1, 6, 8, 1, 8, 1, 8, 13, 17, 13, 12, 13, 17, 13, 6, 12, 8, 8, 13, 5, 17, 13, 16, 0, 8, 13, 12, 13, 13, 11, 16, 6, 8, 1, 6, 0, 8, 1, 2, 0, 8, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
101
[ "The", "other", "proteins", "involved", "in", "the", "ABA", "pathway", "include", "an", "ABA", "receptor", ",", "the", "H", "subunit", "of", "Mg", "-", "chelatase", "(", "CHLH", ")", ",", "and", "the", "regulatory", "component", "of", "ABA", "ABA", "(", "RCAR", ")", "." ]
[ 6, 0, 8, 16, 1, 6, 12, 8, 16, 6, 12, 8, 13, 6, 8, 8, 1, 8, 13, 8, 13, 12, 13, 13, 5, 6, 0, 8, 1, 12, 12, 13, 12, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 3, 4, 4, 4, 4, 1, 0, 1, 0, 0 ]
102
[ "DENV", ",", "dengue", "virus", ";", "IRR", ",", "incidence", "rate", "ratio", ";", "ZIKV", ",", "Zika", "virus", "." ]
[ 12, 13, 8, 8, 13, 12, 13, 8, 8, 8, 13, 12, 13, 12, 8, 13 ]
[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 0 ]
103
[ "Major", "depressive", "disorder", "(", "MDD", ")", "is", "a", "disabling", "illness", ",", "affecting", "a", "high", "proportion", "of", "individuals", "at", "some", "point", "in", "their", "life", "[", "1", "]", "." ]
[ 0, 0, 8, 13, 12, 13, 3, 6, 16, 8, 13, 16, 6, 0, 8, 1, 8, 1, 6, 8, 1, 11, 8, 13, 9, 13, 13 ]
[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
104
[ "Cells", "were", "stained", "with", "primary", "antibodies", "in", "blocking", "solution", "(", "1:100", ")", "for", "2", "h", "at", "4", "°", "C", "and", "washed", "three", "times", "with", "PBS", ".", "Staining", "was", "visualized", "using", "Alexa", "Fluor", "488", "goat", "antirabbit", "and", "Alexa", "Fluor", "594", "goat", "antimouse", "(", "Invitrogen", ")", "secondary", "antibodies", "(", "1:1000", ")", "in", "dark", "condition", "for", "1", "h", "at", "4", "°", "C", "and", "washed", "three", "times", "with", "PBS", ".", "Nuclei", "were", "stained", "using", "4ʹ,6", "-", "diamidino-2", "-", "phenylindole", "(", "DAPI", ")", "(", "contained", "mounting", "solution", ")", ",", "and", "stained", "cells", "were", "viewed", "under", "a", "confocal", "laser", "scanning", "microscope", "." ]
[ 8, 3, 16, 1, 0, 8, 1, 16, 8, 13, 9, 13, 1, 9, 8, 1, 9, 8, 8, 5, 16, 9, 8, 1, 12, 13, 8, 3, 16, 16, 12, 12, 9, 8, 8, 5, 12, 12, 9, 8, 8, 13, 12, 13, 0, 8, 13, 9, 13, 1, 0, 8, 1, 9, 8, 1, 9, 8, 8, 5, 16, 9, 8, 1, 12, 13, 8, 3, 16, 16, 9, 13, 8, 13, 8, 13, 12, 13, 13, 16, 16, 8, 13, 13, 5, 16, 8, 3, 16, 1, 6, 0, 8, 16, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
105
[ "We", "performed", "mRNA", "sequencing", "(", "mRNA-seq", ")", "of", "ovaries", "for", "D.", "simulans", "strain", "w501", "as", "well", "as", "5", "DGRP", "strains", "whose", "median", "nxf2", "expression", "level", "is", "similar", "to", "that", "of", "the", "population", "as", "a", "whole", "based", "on", "the", "DGRP", "microarray", "data", "(", "S16", "Fig", ")", "." ]
[ 11, 16, 8, 8, 13, 12, 13, 1, 8, 1, 12, 12, 8, 12, 1, 2, 1, 9, 12, 8, 6, 0, 8, 8, 8, 3, 0, 1, 11, 1, 6, 8, 1, 6, 8, 16, 1, 6, 12, 8, 8, 13, 12, 12, 13, 13 ]
[ 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
106
[ "Down", "syndrome", "(", "DS", ")", "is", "the", "most", "common", "genetic", "form", "of", "intellectual", "disability", "caused", "by", "the", "complete", "or", "partial", "trisomy", "of", "human", "chromosome", "21", "(", "HSA21)[1", "]", "." ]
[ 12, 8, 13, 12, 13, 3, 6, 2, 0, 0, 8, 1, 0, 8, 16, 1, 6, 0, 5, 0, 8, 1, 0, 8, 9, 13, 12, 13, 13 ]
[ 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0 ]
107
[ "Overall", ",", "the", "operational", "separation", "of", "IDPRs", "from", "IDPs", "is", "relevant", "towards", "correct", "estimates", "of", "the", "occurrence", "of", "intrinsically", "disordered", "proteins", "in", "genome", "-", "wide", "studies", "and", "in", "the", "understanding", "of", "the", "functional", "spectra", "associated", "to", "different", "flavors", "of", "protein", "disorder", "." ]
[ 2, 13, 6, 0, 8, 1, 12, 1, 12, 3, 0, 1, 0, 8, 1, 6, 8, 1, 2, 0, 8, 1, 8, 13, 0, 8, 5, 1, 6, 8, 1, 6, 0, 8, 16, 1, 0, 8, 1, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
108
[ "To", "prevent", "opportunistic", "infections", ",", "the", "World", "Health", "Organization", "(", "WHO", ")", "recommends", "cotrimoxazole", "(", "CTX", ")", "prophylaxis", "for", "HIV", "-", "infected", "individuals", "." ]
[ 10, 16, 0, 8, 13, 6, 12, 12, 12, 13, 12, 13, 16, 8, 13, 12, 13, 8, 1, 12, 13, 16, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
109
[ "The", "adjusted", "male", "median", "(", "AMM", ")", "was", "calculated", "per", "site", "and", "defined", "as", "100", "%", "G6PD", "activity", "." ]
[ 6, 0, 0, 8, 13, 12, 13, 3, 16, 1, 8, 5, 16, 1, 9, 8, 8, 8, 13 ]
[ 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
110
[ "Higher", "BMIGPS", "was", "associated", "with", "lower", "odds", "of", "preparing", "dinner", "at", "home", "(", "Q4", "odds", "ratio", "[", "OR", "]", "=", "0.3", "[", "95", "%", "CI", "0.1–0.9", "]", ";", "P", "=", "0.03", ")", ",", "and", "no", "significant", "associations", "between", "the", "BMI97", "genetic", "scores", "and", "meal", "skipping", "or", "meals", "prepared", "at", "home", "were", "observed", "(", "Fig", "4", ")", "." ]
[ 0, 12, 3, 16, 1, 0, 8, 1, 16, 8, 1, 8, 13, 9, 8, 8, 13, 12, 13, 8, 9, 13, 9, 8, 12, 9, 13, 13, 8, 8, 9, 13, 13, 5, 6, 0, 8, 1, 6, 9, 0, 8, 5, 8, 8, 5, 8, 16, 1, 8, 3, 16, 13, 12, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
111
[ "There", "is", "a", "paucity", "of", "literature", "examining", "how", "both", "community", "members", "and", "health", "care", "professionals", "(", "HCPs", ")", "understand", "potential", "causes", "and", "solutions", "for", "these", "barriers", ",", "particularly", "in", "non", "-", "urban", "settings", "." ]
[ 11, 16, 6, 8, 1, 8, 16, 14, 5, 8, 8, 5, 8, 8, 8, 13, 12, 13, 16, 0, 8, 5, 8, 1, 6, 8, 13, 2, 1, 0, 0, 0, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
112
[ "PedsQL", ":", "Pediatric", "Quality", "of", "Life", "Inventory" ]
[ 12, 13, 0, 8, 1, 8, 8 ]
[ 1, 0, 3, 4, 4, 4, 4 ]
113
[ "Twenty", "-", "seven", "patients", "in", "each", "group", "had", "AIDS", ";", "the", "others", "were", "HIV", "-", "infected", "but", "did", "not", "have", "AIDS", ".", "The", "researchers", "calculated", "costs", "per", "patient", "year", "(", "PPY", ")", "and", "per", "life", "-", "year", "gained", "(", "LYG", ")", ",", "i.e.", ",", "the", "total", "cost", "divided", "by", "the", "number", "of", "extra", "years", "the", "treated", "patients", "lived", "." ]
[ 9, 13, 9, 8, 1, 6, 8, 16, 12, 13, 6, 8, 3, 12, 13, 16, 5, 3, 10, 16, 12, 13, 6, 8, 16, 8, 1, 8, 8, 13, 12, 13, 5, 1, 8, 13, 8, 16, 13, 12, 13, 13, 17, 13, 6, 0, 8, 16, 1, 6, 8, 1, 0, 8, 6, 16, 8, 16, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
114
[ "The", "characterization", "factor", "for", "ozone", "depletion", "is", "based", "on", "the", "ozone", "depletion", "potential", "(", "ODP", ")", "of", "each", "pollutant", ",", "and", "causally", "linked", "to", "the", "incidence", "of", "skin", "cancer", "due", "to", "reduced", "absorption", "of", "ultraviolet", "(", "UV", ")", "radiation", "by", "the", "stratospheric", "ozone", "layer", "." ]
[ 6, 8, 8, 1, 8, 8, 3, 16, 1, 6, 8, 8, 8, 13, 12, 13, 1, 6, 8, 13, 5, 2, 16, 1, 6, 8, 1, 8, 8, 1, 1, 16, 8, 1, 0, 13, 12, 13, 8, 1, 6, 0, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
115
[ "This", "possible", "association", "with", "rs909253", ",", "and", "with", "two", "further", "SNPs", "(", "rs1800683", "and", "rs1041981", ")", "in", "near", "-", "perfect", "linkage", "disequilibrium", "(", "LD", ")", "with", "it", ",", "was", "subsequently", "replicated", "by", "the", "same", "investigators", "in", "a", "further", "1,133", "MI", "cases", "and", "1,006", "controls", "." ]
[ 6, 0, 8, 1, 9, 13, 5, 1, 9, 0, 12, 13, 8, 5, 8, 13, 1, 2, 13, 0, 8, 8, 13, 12, 13, 1, 11, 13, 3, 2, 16, 1, 6, 0, 8, 1, 6, 0, 9, 12, 8, 5, 9, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0 ]
116
[ "d.f", ".", ",", "degrees", "of", "freedom", ";", "F", "statistics", ",", "F", "value", "by", "permutation", ";", "MS", ",", "mean", "squares", ";", "OLS", ",", "ordinary", "least", "squares", ";", "RRPP", ",", "residual", "randomization", "permutation", "procedure", ";", "R2", ",", "coefficient", "of", "determination", ";", "SS", ",", "sequential", "sums", "of", "squares", ";", "Z", ",", "effect", "size", "." ]
[ 8, 13, 13, 8, 1, 8, 13, 12, 8, 13, 12, 8, 1, 8, 13, 12, 13, 8, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 0, 8, 8, 8, 13, 8, 13, 8, 1, 8, 13, 12, 13, 0, 8, 1, 8, 13, 8, 13, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
117
[ "While", "many", "authors", "have", "claimed", "that", "observations", "from", "the", "yeast", "protein", "–", "protein", "interaction", "(", "PPI", ")", "network", "support", "the", "above", "hypothesis", ",", "the", "observed", "structural", "modularity", "may", "be", "an", "artifact", "because", "the", "current", "PPI", "data", "include", "interactions", "inferred", "from", "protein", "complexes", "through", "approaches", "that", "create", "modules", "(", "e.g.", ",", "assigning", "pairwise", "interactions", "among", "all", "proteins", "in", "a", "complex", ")", "." ]
[ 14, 0, 8, 3, 16, 11, 8, 1, 6, 8, 8, 13, 8, 8, 13, 12, 13, 8, 16, 6, 0, 8, 13, 6, 16, 0, 8, 3, 3, 6, 8, 14, 6, 0, 12, 8, 16, 8, 16, 1, 8, 8, 1, 8, 11, 16, 8, 13, 17, 13, 16, 0, 8, 1, 6, 8, 1, 6, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
118
[ "NEP", ":", "neutral", "endopeptidase", "." ]
[ 12, 13, 0, 8, 13 ]
[ 1, 0, 3, 4, 0 ]
119
[ "Each", "SPI", "encodes", "a", "membrane", "-", "associated", "type", "III", "secretion", "system", "(", "T3SS", ")", ",", "which", "promotes", "the", "translocation", "of", "several", "virulence", "effector", "proteins", "believed", "to", "contribute", "to", "bacterial", "entry", "into", "and", "replication", "within", "host", "cells", "[", "11", "]", "." ]
[ 6, 12, 16, 6, 8, 13, 16, 8, 9, 8, 8, 13, 12, 13, 13, 11, 16, 6, 8, 1, 0, 8, 8, 8, 16, 1, 16, 1, 0, 8, 1, 5, 8, 1, 8, 8, 13, 9, 13, 13 ]
[ 0, 1, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
120
[ "CD11c+CD11b-", "cells", "were", "the", "dominant", "populations", "in", "controls", "(", "Ct", ")", "." ]
[ 8, 8, 3, 6, 0, 8, 1, 8, 13, 12, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0 ]
121
[ "Terminal", "deoxynucleotidyl", "transferase", "deoxyuridine", "triphosphate", "nick", "end", "labeling", "(", "TUNEL", ")", "staining", "was", "performed", "to", "examine", "apoptosis", "of", "the", "corneal", "epithelium", "[", "32,33", "]", "using", "an", "Apo", "-", "BrdU", "-", "IHCTM", "In", "Situ", "DNA", "Fragmentation", "Assay", "Kit", "following", "the", "supplier", "’s", "recommendations", "(", "BioVision", ",", "Milpitas", ",", "CA", ",", "USA", ")", "." ]
[ 0, 8, 8, 8, 8, 8, 8, 8, 13, 12, 13, 8, 3, 16, 10, 16, 8, 1, 6, 0, 8, 17, 17, 17, 16, 6, 12, 13, 12, 13, 12, 1, 12, 12, 12, 12, 12, 16, 6, 8, 10, 8, 13, 12, 13, 12, 13, 12, 13, 12, 13, 13 ]
[ 3, 4, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
122
[ "(", "A", ")", "Progeny", "produced", "by", "α", "-", "α", "unisexual", "reproduction", "of", "strain", "XL280", "in", "solo", "cultures", "were", "grown", "in", "10", "-", "fold", "serial", "dilution", "assays", "and", "under", "the", "following", "conditions", ":", "YPD", "at", "30", "°", "C", "for", "2", "d", ";", "YPD", "at", "37", "°", "C", "for", "2", "d", ";", "YPD", "plus", "1", "µg", "/", "mL", "FK506", "at", "30", "°", "C", "for", "2", "d", ";", "YPD", "plus", "8", "µg", "/", "mL", "fluconazole", "(", "FLC", ")", "at", "30", "°", "C", "for", "6", "d", ";", "NS", "(", "melanin", "-", "inducing", "media", ")", "at", "30", "°", "C", "for", "3", "d", ";", "and", "V8", "pH", "=", "7", "(", "mating", "-", "inducing", "media", ")", "at", "room", "temperature", "for", "11", "d.", "(", "B", ")", "Diploid", "progeny", "were", "generated", "infrequently", "following", "unisexual", "reproduction", "." ]
[ 13, 17, 13, 8, 16, 1, 13, 13, 13, 0, 8, 1, 8, 12, 1, 0, 8, 3, 16, 1, 9, 13, 0, 0, 8, 8, 5, 1, 6, 16, 8, 13, 12, 1, 9, 8, 8, 1, 9, 8, 13, 12, 1, 9, 8, 8, 1, 9, 8, 13, 12, 5, 9, 8, 15, 8, 12, 1, 9, 8, 8, 1, 9, 8, 13, 12, 5, 9, 8, 15, 8, 8, 13, 12, 13, 1, 9, 8, 8, 1, 9, 8, 13, 12, 13, 8, 13, 16, 8, 13, 1, 9, 8, 8, 1, 9, 8, 13, 5, 8, 8, 15, 9, 13, 8, 13, 16, 8, 13, 1, 8, 8, 1, 9, 13, 13, 17, 13, 8, 8, 3, 16, 2, 16, 0, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
123
[ "Spinal", "muscular", "atrophy", "(", "SMA", ")", "is", "a", "potentially", "fatal", "neurodegenerative", "disorder", "caused", "by", "the", "systemic", "depletion", "of", "the", "ubiquitously", "expressed", "survival", "motor", "neuron", "(", "SMN", ")", "protein", "[", "1", "]", "." ]
[ 0, 0, 8, 13, 12, 13, 3, 6, 2, 0, 0, 8, 16, 1, 6, 0, 8, 1, 6, 2, 16, 8, 8, 8, 13, 12, 13, 8, 13, 9, 13, 13 ]
[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]
124
[ "Consequently", ",", "the", "increase", "on", "the", "level", "of", "ROS", "results", "to", "the", "increased", "production", "of", "NO", "through", "the", "nitrate", "reductase", "1", "(", "NIA1", ")", "[", "19–21", "]", "." ]
[ 2, 13, 6, 8, 1, 6, 8, 1, 12, 16, 1, 6, 16, 8, 1, 12, 1, 6, 8, 8, 9, 13, 12, 13, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]
125
[ "PLS-DA", "=", "partial", "least", "squares", "-", "discriminant", "analysis", "." ]
[ 12, 13, 0, 0, 8, 13, 0, 8, 13 ]
[ 1, 0, 3, 4, 4, 4, 4, 4, 0 ]
126
[ "Transfusion", "modalities", "included", "either", ":", "1", ")", "simple", "transfusion", "(", "ST", ")", "of", "10–15", "mL", "/", "kg", "RBCs", "with", "the", "post", "-", "transfusion", "Hb", "goal", "of", "11.5–12.0", "g", "/", "dL", ";", "2", ")", "partial", "manual", "exchange", "transfusion", "(", "PME", "):", "removal", "of", "5–8", "mL", "/", "kg", "of", "whole", "blood", "prior", "to", "transfusion", "of", "10–15", "mL", "/", "kg", "RBCs", "with", "the", "post", "-", "transfusion", "Hb", "goal", "of", "11.5–12.0", "g", "/", "dL", ";", "or", "3", ")", "automated", "RBC", "exchange", "(", "1", ")", "with", "the", "post", "-", "transfusion", "goal", "of", "25–30", "%", "fraction", "of", "cells", "remaining", "and", "Hb", "approximately", "0–2", "g", "/", "dL", "above", "the", "pre", "-", "transfusion", "Hb", ".", "All", "RBC", "units", "were", "pre", "-", "storage", "leukoreduced", ",", "sickle", "-", "negative", ",", "ABO", "/", "Rh", "compatible", ",", "C", "/", "c", ",", "E", "/", "e", ",", "and", "Kell", "matched", "with", "additional", "antigenic", "matching", "dependent", "on", "alloantibody", "identification", "." ]
[ 8, 8, 16, 5, 13, 17, 13, 0, 0, 13, 12, 13, 1, 9, 8, 15, 8, 8, 1, 6, 0, 13, 0, 8, 8, 1, 9, 8, 15, 8, 13, 17, 13, 0, 0, 8, 0, 13, 12, 13, 8, 1, 9, 8, 15, 8, 1, 0, 8, 2, 1, 0, 1, 9, 8, 15, 8, 8, 1, 6, 0, 13, 0, 8, 8, 1, 9, 8, 15, 8, 13, 5, 17, 13, 16, 12, 8, 13, 17, 13, 1, 6, 0, 13, 0, 8, 1, 9, 8, 8, 1, 8, 16, 5, 8, 2, 9, 8, 15, 8, 1, 6, 0, 13, 0, 8, 13, 6, 12, 8, 3, 0, 13, 0, 0, 13, 8, 13, 0, 13, 8, 15, 8, 0, 13, 8, 15, 8, 13, 8, 15, 8, 13, 5, 12, 16, 1, 0, 0, 8, 0, 1, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
127
[ "Generalized", "Estimating", "Equations", "(", "GEE", ")", "with", "exchangeable", "correlation", "structure", "was", "used", "to", "take", "into", "account", "repeated", "measurements", "at", "different", "ages", "of", "the", "infant", "." ]
[ 16, 12, 8, 13, 12, 13, 1, 0, 8, 8, 3, 16, 10, 16, 1, 8, 16, 8, 1, 0, 8, 1, 6, 8, 13 ]
[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
128
[ "Zero", "-", "inflated", "Poisson", "(", "ZIP", ")", "regression", "analysis", "was", "conducted", "to", "evaluate", "the", "impact", "of", "providing", "HIVST", "kits", "on", "HIV", "testing", "coverage", "and", "frequency", "among", "MSM", "participants", "and", "their", "partners", "by", "adjusting", "for", "potential", "confounders", ",", "including", "subgroup", ",", "age", ",", "ethnicity", ",", "residence", ",", "cohabitation", ",", "duration", "of", "living", "in", "a", "study", "city", ",", "education", "level", ",", "sexual", "orientation", ",", "marital", "status", ",", "occupation", ",", "and", "monthly", "personal", "income", "." ]
[ 9, 13, 16, 12, 13, 12, 13, 8, 8, 3, 16, 10, 16, 6, 8, 1, 16, 12, 8, 1, 12, 8, 8, 5, 8, 1, 12, 8, 5, 11, 8, 1, 16, 1, 0, 8, 13, 16, 8, 13, 8, 13, 8, 13, 8, 13, 8, 13, 8, 1, 8, 1, 6, 8, 8, 13, 8, 8, 13, 0, 8, 13, 0, 8, 13, 8, 13, 5, 0, 0, 8, 13 ]
[ 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
129
[ "The", "audiological", "evaluation", "included", "standard", "pure", "-", "tone", "audiometry", "(", "air", "conduction", "AC", ":", "0.25", "through", "8", "kHz", ";", "bone", "conduction", "BC", ":", "0.5", "through", "6", "kHz", ")", ",", "conducted", "with", "a", "clinical", "audiometer", "in", "5", "-", "dB", "steps", "." ]
[ 6, 0, 8, 16, 0, 0, 13, 8, 8, 13, 8, 8, 12, 13, 9, 1, 9, 8, 13, 8, 8, 12, 13, 9, 1, 9, 8, 13, 13, 16, 1, 6, 0, 8, 1, 9, 13, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 1, 0, 0, 0, 0, 0, 0, 3, 4, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
130
[ "Here", "we", "show", "that", "mPRβ", "has", "a", "cytosolic", "N", "-", "terminus", "and", "an", "extracellular", "C", "-", "terminus", ",", "a", "topology", "that", "matches", "the", "AdipoR", "and", "is", "opposite", "to", "that", "of", "GPCRs", ".", "We", "further", "demonstrate", "that", "mPRβ", "signals", "through", "APPL1", "(", "Adapter", "protein", "containing", "Pleckstrin", "homology", "domain", ",", "Phosphotyrosine", "binding", "domain", "and", "Leucine", "zipper", "motif", "1", ")", "and", "its", "interacting", "partner", ",", "the", "serine", "/", "threonine", "kinase", "Akt2", "(", "also", "known", "as", "protein", "kinase", "B", ")", ".", "Interestingly", ",", "mPRβ", "signaling", "requires", "endocytosis", "through", "the", "clathrin", "pathway", ",", "a", "process", "that", "depends", "on", "APPL1", ".", "mPR", "associates", "with", "APPL1", "and", "Akt2", "into", "signaling", "endosomes", "minutes", "after", "P4", "addition", "." ]
[ 2, 11, 16, 11, 8, 16, 6, 0, 8, 13, 8, 5, 6, 0, 8, 13, 8, 13, 6, 8, 11, 16, 6, 12, 5, 3, 0, 1, 11, 1, 12, 13, 11, 2, 16, 11, 8, 16, 1, 12, 13, 8, 8, 16, 12, 8, 8, 13, 8, 16, 8, 5, 8, 8, 8, 9, 13, 5, 11, 16, 8, 13, 6, 8, 15, 8, 8, 12, 13, 2, 16, 1, 8, 8, 12, 13, 13, 2, 13, 8, 16, 16, 8, 1, 6, 8, 8, 13, 6, 8, 11, 16, 1, 12, 13, 12, 16, 1, 12, 5, 12, 1, 16, 8, 8, 1, 12, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0 ]
131
[ "Such", "mechanical", "action", "induces", "the", "activation", "of", "endothelial", "nitric", "oxide", "synthase", "(", "eNOS", ")", ",", "which", "in", "turn", "produces", "NO", ".", "The", "reduction", "in", "the", "calcium", "influx", "into", "smooth", "muscle", "cells", "that", "cause", "contraction", "and", ",", "an", "increase", "in", "the", "calcium", "concentration", "in", "endothelial", "cells", "increasing", "the", "phosphorylation", "of", "eNOS", "has", "been", "reported", "to", "be", "other", "important", "effects", "related", "to", "ET", "on", "the", "vessels", "[", "33,34", "]", "." ]
[ 0, 0, 8, 16, 6, 8, 1, 0, 8, 8, 8, 13, 12, 13, 13, 11, 1, 8, 16, 12, 13, 6, 8, 1, 6, 8, 8, 1, 0, 8, 8, 11, 16, 8, 5, 13, 6, 8, 1, 6, 8, 8, 1, 0, 8, 16, 6, 8, 1, 12, 3, 3, 16, 1, 3, 0, 0, 8, 16, 1, 12, 1, 6, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
132
[ "For", "instance", ",", "loss", "of", "the", "H3K27", "methyltransferase", "Enhancer", "of", "Zeste", "2", "(", "EZH2", ")", "causes", "early", "post", "-", "implantation", "embryonic", "lethality", "[", "32", "]", "." ]
[ 1, 8, 13, 8, 1, 6, 8, 8, 12, 1, 12, 9, 13, 12, 13, 16, 0, 0, 0, 0, 0, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
133
[ "This", "center", "is", "dedicated", "to", "the", "diagnosis", ",", "treatment", ",", "and", "follow", "-", "up", "of", "patients", "with", "transient", "ischemic", "attack", "(", "TIA", ")", "and", "post", "-", "acute", "stroke", ",", "patients", "with", "chronic", "subcortical", "cerebrovascular", "disease", "without", "any", "history", "of", "stroke", ",", "and", "patients", "with", "vascular", "-", "related", "cognitive", "impairment", "(", "from", "mild", "[", "VCI", "]", "to", "severe", "forms", "[", "VaD", "and", "its", "subtypes", "]", ")", "." ]
[ 6, 8, 3, 16, 1, 6, 8, 13, 8, 13, 5, 8, 13, 1, 1, 8, 1, 0, 0, 8, 13, 12, 13, 5, 0, 13, 0, 8, 13, 8, 1, 0, 0, 0, 8, 1, 6, 8, 1, 8, 13, 5, 8, 1, 8, 13, 16, 0, 8, 13, 1, 0, 17, 12, 13, 1, 0, 8, 17, 12, 5, 11, 8, 13, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
134
[ "The", "Centers", "for", "Disease", "Control", "and", "Prevention", "(", "CDC", ")", "has", "been", "monitoring", "invasive", "pneumococcal", "disease", "since", "1995", "through", "the", "Active", "Bacterial", "Core", "(", "ABC", ")", "surveillance", "program", "[", "6,14,30", "]", "and", "as", "a", "result", ",", "the", "post", "-", "vaccination", "increase", "in", "nonvaccine", "serotype", "19A", "disease", "in", "the", "US", "was", "quickly", "detected", "." ]
[ 6, 12, 1, 12, 12, 5, 12, 13, 12, 13, 3, 3, 16, 0, 0, 8, 14, 9, 1, 6, 12, 12, 12, 13, 12, 13, 8, 8, 17, 17, 17, 5, 1, 6, 8, 13, 6, 0, 0, 0, 8, 1, 0, 8, 9, 8, 1, 6, 12, 3, 2, 16, 13 ]
[ 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
135
[ "We", "also", "aimed", "to", "analyse", "the", "impact", "of", "therapy", "-", "related", "factors", "(", "i.e.", ",", "local", "radiotherapy", "[", "LRT", "]", ",", "CSI", ",", "MTXi.vt", ".", ")", "as", "well", "as", "age", ",", "gender", ",", "or", "time", "since", "surgery", "on", "the", "IQ", "profiles", "of", "patients", "by", "comparing", "outcomes", "in", "the", "prospective", "HIT2000", "/", "HIT", "trials", "." ]
[ 11, 2, 16, 10, 16, 6, 8, 1, 8, 13, 16, 8, 13, 17, 13, 0, 8, 13, 12, 13, 13, 12, 13, 12, 13, 13, 1, 2, 1, 8, 13, 8, 13, 5, 8, 14, 8, 1, 6, 8, 8, 1, 8, 1, 16, 8, 1, 6, 0, 12, 15, 12, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0 ]
136
[ "Reportedly", ",", "Schisandra", "chinensis", "(", "SC", ")", "has", "long", "been", "used", "as", "a", "tonic", ",", "sedative", ",", "astringent", ",", "anti", "-", "aging", "agent", ",", "and", "to", "treat", "cardiovascular", "symptoms", "in", "Korea", ",", "China", "and", "Japan", "[", "39,40", "]", "." ]
[ 2, 13, 12, 12, 13, 12, 13, 3, 2, 3, 16, 1, 6, 8, 13, 8, 13, 8, 13, 0, 0, 0, 8, 13, 5, 10, 16, 0, 8, 1, 12, 13, 12, 5, 12, 13, 9, 13, 13 ]
[ 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
137
[ "Lung", "cancer", "in", "Xuanwei", "(", "LCXW", ")", ",", "China", ",", "is", "known", "throughout", "the", "world", "for", "its", "distinctive", "characteristics", ",", "but", "little", "is", "known", "about", "its", "pathogenesis", "." ]
[ 8, 8, 1, 12, 13, 12, 13, 13, 12, 13, 3, 16, 1, 6, 8, 1, 11, 0, 8, 13, 5, 0, 3, 16, 1, 11, 8, 13 ]
[ 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
138
[ "Patient", "Activation", "Measure", "(", "PAM", ")", "is", "a", "tool", "for", "measuring", "the", "level", "of", "patient", "engagement", "in", "their", "own", "healthcare", "and", "consists", "of", "13", "items", "assessing", "knowledge", ",", "skills", "and", "confidence", "in", "self", "-", "care", "[", "22", "]", "." ]
[ 12, 12, 12, 13, 12, 13, 3, 6, 8, 1, 16, 6, 8, 1, 8, 8, 1, 11, 0, 8, 5, 16, 1, 9, 8, 16, 8, 13, 8, 5, 8, 1, 8, 13, 8, 13, 9, 13, 13 ]
[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
139
[ "We", "selectively", "opted", "to", "study", "the", "response", "to", "the", "measles", ",", "mumps", "and", "rubella", "(", "MMR", ")", "vaccine", "for", "the", "following", "reasons", ":", "this", "trivalent", "vaccine", "is", "routinely", "administered", "in", "the", "province", "of", "Québec", ",", "it", "triggers", "a", "durable", "humoral", "immune", "response", "with", "a", "high", "rate", "of", "responders", "[", "19", "]", ",", "there", "is", "a", "robust", "assay", "to", "quantify", "antibodies", "to", "MMR", "[", "20", "]", ",", "and", "the", "MMR", "vaccine", "provides", "efficient", "protection", "to", "these", "three", "viruses", "[", "21–23", "]", "." ]
[ 11, 2, 16, 1, 16, 6, 8, 1, 6, 8, 13, 8, 5, 8, 13, 12, 13, 8, 1, 6, 0, 8, 13, 6, 8, 8, 16, 2, 16, 1, 6, 8, 1, 12, 13, 11, 16, 6, 0, 0, 0, 8, 1, 6, 0, 8, 1, 8, 13, 9, 13, 13, 11, 16, 6, 0, 8, 1, 16, 8, 1, 12, 13, 9, 13, 13, 5, 6, 12, 8, 16, 0, 8, 1, 6, 9, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
140
[ "The", "aim", "of", "this", "study", "was", "to", "produce", "antibodies", "against", "parvalbumins", "as", "recombinant", "single", "chain", "variable", "fragments", "(", "scFv", ")", "by", "phage", "display", "technology", "." ]
[ 6, 8, 1, 6, 8, 3, 10, 16, 8, 1, 8, 1, 0, 0, 8, 0, 8, 13, 12, 13, 1, 12, 12, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0 ]
141
[ "Two", "-", "color", "TIRF", "microscopy", "was", "used", "to", "analyze", "COS", "cells", "coexpressing", "KHC(1", "-", "560)-3xmCit", "with", "a", "mCherry", "-", "labeled", "version", "of", "the", "+", "TIP", "protein", "end", "binding", "(", "EB)3", "[", "22", "]", "." ]
[ 9, 13, 8, 12, 8, 3, 16, 10, 16, 12, 8, 16, 12, 13, 8, 1, 6, 8, 13, 16, 8, 1, 6, 8, 8, 8, 8, 8, 13, 12, 13, 9, 13, 13 ]
[ 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0 ]
142
[ "BMI", ",", "body", "mass", "index", ";", "WHtR", ",", "waist", "-", "to", "-", "height", "ratio", "." ]
[ 12, 13, 8, 8, 8, 13, 12, 13, 8, 13, 1, 13, 8, 8, 13 ]
[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 4, 0 ]
143
[ "RT-qPCR", ",", "quantitative", "reverse", "transcription", "PCR", "." ]
[ 12, 13, 0, 0, 8, 8, 13 ]
[ 1, 0, 3, 4, 4, 4, 0 ]
144
[ "The", "random", "forest", "model", "exhibited", "the", "best", "performance", "at", "all", "time", "-", "points", "with", "an", "area", "under", "the", "receiver", "operating", "characteristic", "curve", "(", "AUC", ")", "of", "0.64", ",", "0.68", ",", "and", "0.7", "at", "6", "-", "months", ",", "12", "-", "months", ",", "and", "24", "-", "months", "respectively", "." ]
[ 6, 0, 8, 8, 16, 6, 0, 8, 1, 6, 8, 13, 8, 1, 6, 8, 1, 6, 8, 16, 8, 8, 13, 12, 13, 1, 9, 13, 9, 13, 5, 9, 1, 9, 13, 8, 13, 9, 13, 8, 13, 5, 9, 13, 8, 2, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
145
[ "One", "such", "antigen", "that", "shows", "promise", "as", "a", "vaccine", "candidate", "is", "apical", "membrane", "antigen", "1", "(", "AMA1", ")", "." ]
[ 9, 0, 8, 11, 16, 8, 1, 6, 8, 8, 3, 0, 8, 8, 9, 13, 12, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0 ]
146
[ "Table", "3", "presents", "the", "crude", "and", "adjusted", "analysis", "of", "factors", "associated", "with", "GXN", ".", "In", "crude", "analysis", ",", "socioeconomic", "variables", "(", "wealth", "index", ",", "beneficiary", "of", "cash", "transfer", "program", ",", "maternal", "schooling", "and", "number", "of", "people", "in", "the", "house", ")", "were", "associated", "to", "higher", "risk", "for", "gestational", "night", "blindness", "when", "compared", "to", "reference", "strata", "for", "better", "life", "conditions", "." ]
[ 8, 9, 16, 6, 0, 5, 16, 8, 1, 8, 16, 1, 12, 13, 1, 0, 8, 13, 0, 8, 13, 8, 8, 13, 8, 1, 8, 8, 8, 13, 0, 8, 5, 8, 1, 8, 1, 6, 8, 13, 3, 16, 1, 0, 8, 1, 0, 8, 8, 14, 16, 1, 8, 8, 1, 0, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
147
[ "Nevertheless", ",", "CBM124", "was", "unable", "to", "nodulate", "the", "C.", "taiwanensis", "legume", "host", "Mimosa", "pudica", "and", "retained", "the", "pathogenic", "properties", "of", "R.", "solanacearum", ",", "i.e.", ",", "pathogenicity", "on", "Arabidopsis", "thaliana", "and", "hypersensitive", "response", "(", "HR", ")", "induction", "on", "tobacco", "(", "Figure", "S2", ")", "." ]
[ 2, 13, 12, 3, 0, 10, 16, 6, 12, 8, 8, 8, 12, 12, 5, 16, 6, 0, 8, 1, 8, 8, 13, 17, 13, 8, 1, 12, 8, 5, 0, 8, 13, 12, 13, 8, 1, 8, 13, 12, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
148
[ "Obesity", "is", "a", "major", "risk", "factor", "for", "GDM[5", "]", ",", "and", "26", "%", "of", "the", "women", "in", "this", "study", "developed", "GDM", ".", "Although", "the", "lifestyle", "intervention", "did", "not", "prevent", "the", "2", "primary", "outcomes", "of", "the", "trial", "—", "the", "incidence", "of", "GDM", "and", "large", "-", "for", "-", "gestational", "-", "age", "(", "LGA", ")", "infants", ",", "it", "reduced", "maternal", "glycaemic", "load", ",", "saturated", "fat", "intake", ",", "gestational", "weight", "gain", "and", "adiposity", ",", "and", "improved", "the", "maternal", "metabolome", "[", "35,37", "]", ";", "in", "the", "infants", ",", "adiposity", "at", "age", "6", "months", "was", "reduced", "[", "36", "]", "." ]
[ 8, 3, 6, 0, 8, 8, 1, 12, 13, 13, 5, 9, 8, 1, 6, 8, 1, 6, 8, 16, 12, 13, 14, 6, 8, 8, 3, 10, 16, 6, 9, 0, 8, 1, 6, 8, 13, 6, 8, 1, 12, 5, 0, 13, 1, 13, 0, 13, 8, 13, 12, 13, 8, 13, 11, 16, 0, 0, 8, 13, 16, 8, 8, 13, 0, 8, 8, 5, 8, 13, 5, 16, 6, 0, 8, 13, 9, 13, 13, 1, 6, 8, 13, 8, 1, 8, 9, 8, 3, 16, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
149
[ "Moreover", ",", "roundabouts", "differ", "more", "than", "hundred", "-", "fold", "in", "their", "maximal", "expression", "(", "ME", ")", ",", "that", "is", "the", "highest", "expression", "level", "attained", "in", "any", "tissue-", "or", "cell", "-", "type", "." ]
[ 2, 13, 8, 16, 2, 1, 9, 13, 2, 1, 11, 0, 8, 13, 12, 13, 13, 11, 3, 6, 0, 8, 8, 16, 1, 6, 8, 5, 8, 13, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
150
[ "Dynamic", "time", "warping", "(", "DTW", ")", "was", "used", "for", "computing", "the", "distance", "between", "the", "input", "signals", "and", "the", "stored", "templates", ",", "simulating", "templates", "with", "various", "temporal", "relations", "between", "their", "subparts", "." ]
[ 0, 8, 8, 13, 12, 13, 3, 16, 1, 16, 6, 8, 1, 6, 8, 8, 5, 6, 16, 8, 13, 16, 8, 1, 0, 0, 8, 1, 11, 8, 13 ]
[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
151
[ "To", "activate", "potential", "latency", "complexes", "of", "TGFβ", "present", "in", "conditioned", "SN", ",", "we", "performed", "acidification", "followed", "by", "neutralization", "to", "chemically", "disassemble", "the", "SLC", "(", "Fig", "8E", "and", "8F", ")", ".", "In", "line", "with", "our", "previous", "results", "for", "nonacidified", "conditioned", "SN", ",", "we", "found", "reduced", "bioactivity", "of", "TGFβ", "reporter", "cells", "with", "SN", "from", "BMPR2", "-", "deficient", "cells", ",", "suggesting", "their", "strong", "consumption", "of", "active", "TGFβ", "(", "typically", "delivered", "by", "serum", "supplements", "such", "as", "fetal", "calf", "serum", "[", "FCS", "]", ")", "under", "steady", "-", "state", "conditions", "(", "Fig", "8F", ")", ".", "However", ",", "after", "acidification", ",", "we", "found", "increased", "levels", "of", "active", "TGFβ", "present", "in", "conditioned", "SN", "from", "BMPR2", "-", "deficient", "cells", ",", "which", "confirms", "increased", "accumulation", "of", "de", "novo", "–", "formed", "latency", "complexes", "within", "conditioned", "media", "." ]
[ 10, 16, 0, 8, 8, 1, 12, 0, 1, 16, 12, 13, 11, 16, 8, 16, 1, 8, 10, 2, 16, 6, 12, 13, 8, 9, 5, 9, 13, 13, 1, 8, 1, 11, 0, 8, 1, 0, 16, 12, 13, 11, 16, 16, 8, 1, 12, 8, 8, 1, 12, 1, 12, 13, 0, 8, 13, 16, 11, 0, 8, 1, 0, 12, 13, 2, 16, 1, 8, 8, 0, 1, 0, 8, 8, 17, 12, 13, 13, 1, 0, 13, 8, 8, 13, 8, 9, 13, 13, 2, 13, 1, 8, 13, 11, 16, 16, 8, 1, 0, 12, 0, 1, 16, 12, 1, 12, 13, 0, 8, 13, 11, 16, 16, 8, 1, 17, 17, 13, 16, 8, 8, 1, 16, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
152
[ "Using", "data", "from", "the", "Swedish", "Medical", "Birth", "Register", "(", "MBR", ")", ",", "singleton", "live", "births", "from", "1973", "to", "2012", "were", "identified", "and", "linked", "to", "data", "from", "the", "Swedish", "Renal", "Register", "(", "SRR", ")", "and", "National", "Patient", "Register", "(", "NPR", ";", "up", "to", "2013", ")", "." ]
[ 16, 8, 1, 6, 12, 12, 12, 12, 13, 12, 13, 13, 8, 0, 8, 1, 9, 1, 9, 3, 16, 5, 16, 1, 8, 1, 6, 12, 12, 12, 13, 12, 13, 5, 12, 12, 12, 13, 12, 13, 1, 1, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0 ]
153
[ "ACE", "inhibitors", "(", "ACEIs", ")", "and", "angiotensin", "II", "receptor", "blockers", "(", "ARBs", ")", "decrease", "the", "level", "of", "ACE", "and", "increase", "the", "level", "of", "ACE2", "[", "14", "]", ",", "which", "may", "increase", "the", "risk", "of", "SARS", "-CoV-2", "infection", ",", "which", "may", "be", "the", "reason", "why", "more", "patients", "with", "hypertension", "and", "coronary", "heart", "disease", "also", "had", "lymphopenia", ",", "as", "ACEIs", "and", "ARBs", "are", "commonly", "used", "drugs", "under", "these", "circumstances", "." ]
[ 12, 8, 13, 12, 13, 5, 8, 9, 8, 8, 13, 12, 13, 16, 6, 8, 1, 12, 5, 16, 6, 8, 1, 12, 13, 9, 13, 13, 11, 3, 16, 6, 8, 1, 12, 12, 8, 13, 11, 3, 3, 6, 8, 14, 0, 8, 1, 8, 5, 0, 8, 8, 2, 16, 8, 13, 14, 12, 5, 12, 3, 2, 16, 8, 1, 6, 8, 13 ]
[ 0, 0, 0, 1, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
154
[ "Of", "all", "299", "biopsy", "-", "naive", "men", ",", "full", "data", "on", "PI", "-", "RADSv1.0", ",", "biopsy", "-", "outcome", ",", "PSA", ",", "age", ",", "DRE", ",", "prostate", "volume", "(", "PV", ")", ",", "PSA", "-", "density", ",", "lesions", "on", "TRUS", "and", "the", "European", "Randomised", "Study", "of", "Screening", "for", "Prostate", "Cancer", "Risk", "calculator", "(", "ERSPC", "-", "RC", ")", "3", "were", "available", "for", "293", "men", "(", "160", "from", "Heidelberg", "and", "133", "from", "UCLH", ")", ".", "Those", "samples", "served", "for", "validation", "and", "for", "comparisons", "to", "ERPSC", "-", "RC3", ",", "PI", "-", "RADSv1.0", "and", "combined", "ERSPC", "-", "RC3", "and", "PI", "-", "RADSv1.0", "." ]
[ 1, 6, 9, 8, 13, 0, 8, 13, 0, 8, 1, 12, 13, 8, 13, 8, 13, 8, 13, 12, 13, 8, 13, 12, 13, 8, 8, 13, 12, 13, 13, 12, 13, 8, 13, 8, 1, 12, 5, 6, 12, 12, 12, 1, 12, 1, 12, 12, 12, 12, 13, 12, 13, 12, 13, 9, 3, 0, 1, 9, 8, 13, 9, 1, 12, 5, 9, 1, 12, 13, 13, 6, 8, 16, 1, 8, 5, 1, 8, 1, 12, 13, 12, 13, 12, 13, 8, 5, 0, 12, 13, 12, 5, 12, 13, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 3, 4, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
155
[ "Abbreviations", ":", "ACT", ",", "antenatal", "corticosteroid", "therapy", ";", "PSM", ",", "propensity", "score", "matching", "." ]
[ 8, 13, 12, 13, 0, 8, 8, 13, 12, 13, 8, 8, 8, 13 ]
[ 0, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0 ]
156
[ "Results", "from", "controls", "were", "compared", "to", "sFRP2", "-", "treated", "cells", "using", "analysis", "of", "variance", "(", "ANOVA", ")", "." ]
[ 8, 1, 8, 3, 16, 1, 8, 13, 16, 8, 16, 8, 1, 8, 13, 12, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0 ]
157
[ "For", "instance", ",", "NSUN2", "is", "absent", "in", "quiescent", "stem", "cells", "in", "hair", "follicle", "bulges", "(", "BGs", ")", ",", "steadily", "increases", "in", "progenitor", "cells", "in", "the", "hair", "germ", "(", "HG", ")", ",", "and", "is", "highest", "in", "the", "growing", "(", "anagen", ")", "hair", "bulb", "(", "HB", ")", "(", "Fig", "1A", "and", "1B", ")", "." ]
[ 1, 8, 13, 12, 3, 0, 1, 0, 8, 8, 1, 8, 8, 8, 13, 12, 13, 13, 2, 16, 1, 8, 8, 1, 6, 8, 8, 13, 12, 13, 13, 5, 3, 0, 1, 6, 16, 13, 0, 13, 8, 8, 13, 12, 13, 13, 12, 8, 5, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
158
[ "In", "the", "present", "study", ",", "human", "participants", "completed", "a", "free", "-", "recall", "WM", "task", "while", "electroencephalography", "(", "EEG", ")", "was", "recorded", "(", "Fig", "2", ")", "." ]
[ 1, 6, 0, 8, 13, 0, 8, 16, 6, 0, 13, 16, 12, 8, 14, 8, 13, 12, 13, 3, 16, 13, 12, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0 ]
159
[ "Chromatin", "conformation", "capture", "(", "3C", ")", "was", "performed", "in", "B73", "using", "a", "DpnII", "restriction", "endonuclease", "digestion", "to", "check", "whether", "chromatin", "loops", "were", "formed", "in", "CRM1", "regions", "(", "Figs", "3D", ",", "3E", "and", "S3E", ")", ".", "After", "a", "DpnII", "digestion", ",", "there", "were", "5", "potential", "ligations", ",", "designated", "①+②", ",", "①+③", ",", "②+③", ",", "‘", "①’+②", ",", "and", "‘", "①’+③", "(", "Fig", "3E", ")", ".", "Three", "of", "these", ",", "②+③", ",", "‘", "①’+②", ",", "and", "‘", "①’+③", ",", "were", "detected", "only", "in", "the", "3C", "sample", "and", "not", "in", "undigested", "and", "unligated", "samples", "(", "Fig", "3F", ")", ",", "indicating", "that", "chromatin", "loops", "were", "formed", "." ]
[ 8, 8, 8, 13, 12, 13, 3, 16, 1, 9, 16, 6, 12, 8, 8, 8, 10, 16, 14, 8, 8, 3, 16, 1, 8, 8, 13, 12, 9, 13, 9, 5, 8, 13, 13, 1, 6, 12, 8, 13, 11, 3, 9, 0, 8, 13, 16, 17, 13, 17, 13, 8, 13, 13, 17, 13, 5, 13, 17, 13, 8, 9, 13, 13, 9, 1, 11, 13, 8, 13, 13, 17, 13, 5, 13, 17, 13, 3, 16, 2, 1, 6, 12, 8, 5, 10, 1, 0, 5, 0, 8, 13, 8, 9, 13, 13, 16, 14, 8, 8, 3, 16, 13 ]
[ 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
160
[ "Early", "lesion", "studies", "[", "18", "]", "showed", "that", "whisking", "is", "generated", "independently", "from", "the", "septo", "-", "hippocampal", "system", ";", "instead", ",", "the", "intermediate", "band", "of", "the", "ventral", "intermediate", "reticular", "formation", "(", "vIRt", ")", "is", "critical", "in", "generating", "the", "whisking", "pattern", "[", "58", "]", ".", "vIRt", "functions", "as", "the", "premotor", "pattern", "generator", "for", "rhythmic", "whisking", "and", "is", "part", "of", "a", "larger", "circuit", "devoted", "to", "inspiration", "(", "pre", "-", "Bötzinger", "complex", ")", "." ]
[ 0, 8, 8, 17, 9, 13, 16, 14, 8, 3, 16, 2, 1, 6, 0, 0, 0, 8, 13, 2, 13, 6, 0, 8, 1, 6, 0, 0, 0, 8, 13, 12, 13, 3, 0, 1, 16, 6, 8, 8, 17, 9, 13, 13, 12, 16, 1, 6, 0, 8, 8, 1, 0, 8, 5, 3, 8, 1, 6, 0, 8, 16, 1, 8, 13, 0, 0, 0, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
161
[ "We", "further", "validated", "these", "findings", "by", "bisulfite", "pyrosequencing", "of", "a", "larger", "population", ",", "followed", "by", "determination", "of", "the", "impact", "of", "DNAm", "on", "candidate", "gene", "expression", "and", "the", "impact", "of", "common", "meSNPs", "on", "DNAm", ".", "We", "also", "evaluated", "associations", "between", "DNAm", "-", "modifying", "meSNPs", "(", "known", "as", "methylation", "quantitative", "trait", "locus", "or", "meQTLs", ")", "and", "treatment", "response", "." ]
[ 11, 2, 16, 6, 8, 1, 8, 8, 1, 6, 0, 8, 13, 16, 1, 8, 1, 6, 8, 1, 12, 1, 8, 8, 8, 5, 6, 8, 1, 0, 8, 1, 12, 13, 11, 2, 16, 8, 1, 12, 13, 16, 8, 13, 16, 1, 8, 0, 8, 8, 5, 12, 13, 5, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]
162
[ "Time", "to", "first", "Plasmodium", "infection", "or", "clinical", "episode", "and", "its", "association", "with", "treatment", "and", "covariates", "were", "modelled", "using", "Cox", "regression", ",", "and", "the", "proportional", "hazards", "(", "PH", ")", "assumption", "was", "checked", "using", "the", "test", "based", "on", "the", "Schoenfeld", "residuals", "." ]
[ 8, 1, 0, 8, 8, 5, 0, 8, 5, 11, 8, 1, 8, 5, 8, 3, 16, 16, 12, 8, 13, 5, 6, 0, 8, 13, 12, 13, 8, 3, 16, 16, 6, 8, 16, 1, 6, 12, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
163
[ "The", "unit", "cost", "of", "VMMC", "used", "in", "the", "analysis", "was", "$", "109", "U.S.", "dollars", "(", "USD", ")", ",", "based", "on", "an", "analysis", "conducted", "by", "Population", "Services", "International", "(", "PSI)/Swaziland", ",", "a", "VMMC", "implementer", "in", "the", "country", "(", "all", "subsequent", "references", "to", "currency", "are", "USD", ")", ".", "VMMC", "unit", "cost", "was", "assumed", "to", "be", "constant", "across", "age", "groups", "." ]
[ 6, 8, 8, 1, 12, 16, 1, 6, 8, 3, 15, 9, 12, 8, 13, 12, 13, 13, 16, 1, 6, 8, 16, 1, 12, 12, 12, 13, 12, 13, 6, 12, 8, 1, 6, 8, 13, 6, 0, 8, 10, 8, 3, 12, 13, 13, 12, 8, 8, 3, 16, 10, 3, 0, 1, 8, 8, 13 ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
164
[ "Increased", "muscle", "oxidative", "activity", "is", "typical", "in", "patients", "with", "myopathies", "involving", "muscle", "glycolysis", "or", "glycogenolysis", ",", "including", "phosphofructokinase", "disease", "(", "PFKD", ")", "and", "McArdle", "'s", "disease", "(", "Vissing", "et", "al", ".", "1996", ")", "." ]
[ 16, 8, 0, 8, 3, 0, 1, 8, 1, 8, 16, 8, 8, 5, 8, 13, 16, 8, 8, 13, 12, 13, 5, 12, 10, 8, 13, 12, 12, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
165
[ "The", "model", "framework", "was", "codesigned", "with", "stakeholders", "from", "the", "World", "Health", "Organization", "(", "WHO", ")", ",", "the", "United", "Nations", "Development", "Programme", ",", "the", "Vietnamese", "Ministry", "of", "Health", ",", "the", "Pasteur", "Institute", "Ho", "Chi", "Minh", "City", ",", "the", "Pasteur", "Institute", "Nha", "Trang", ",", "the", "Institute", "of", "Hygiene", "and", "Epidemiology", "Tay", "Nguyen", "(", "TIHE", ")", ",", "and", "the", "National", "Institute", "of", "Hygiene", "and", "Epidemiology", "(", "NIHE", ")", ".", "The", "system", "is", "designed", "to", "generate", "monthly", "estimates", "of", "dengue", "risk", "across", "Vietnam", "(", "331,210", "km2", ")", "at", "the", "province", "level", "(", "n", "=", "63", ")", "in", "near", "-", "real", "time", "(", "i.e.", ",", "current", "time", "minus", "processing", "time", ")", "." ]
[ 6, 8, 8, 3, 16, 1, 8, 1, 6, 12, 12, 12, 13, 12, 13, 13, 6, 12, 12, 12, 12, 13, 6, 12, 12, 1, 12, 13, 6, 12, 12, 12, 12, 12, 12, 13, 6, 12, 12, 12, 12, 13, 6, 12, 1, 12, 5, 12, 12, 12, 13, 12, 13, 13, 5, 6, 12, 12, 1, 12, 5, 12, 13, 12, 13, 13, 6, 8, 3, 16, 10, 16, 0, 8, 1, 8, 8, 1, 12, 13, 9, 9, 13, 1, 6, 8, 8, 13, 8, 15, 9, 13, 1, 2, 13, 0, 8, 13, 17, 13, 0, 8, 5, 8, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
166
[ "The", "primary", "objective", "of", "this", "study", "was", "to", "explore", "the", "relationship", "between", "FVH", "and", "infarct", "morphology", "in", "patients", "with", "symptomatic", "internal", "carotid", "artery", "(", "ICA", ")", "or", "middle", "cerebral", "artery", "(", "MCA", ")", "occlusions", "." ]
[ 6, 0, 8, 1, 6, 8, 3, 10, 16, 6, 8, 1, 12, 5, 0, 8, 1, 8, 1, 0, 0, 0, 8, 13, 12, 13, 5, 0, 0, 8, 13, 12, 13, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0 ]
167
[ "TRAF4", "has", "multiple", "subcellular", "localizations", ":", "to", "the", "plasma", "membrane", "in", "tight", "junctions", "(", "TJs", ")", ",", "cytoplasmic", "and", "nuclear", "." ]
[ 12, 16, 0, 0, 8, 13, 1, 6, 8, 8, 1, 0, 8, 13, 12, 13, 13, 0, 5, 0, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 0, 0, 0 ]
168
[ "E", ",", "embryonic", "day", ";", "H/E", ",", "hematoxylin", "/", "eosin", "stain", ";", "N1RA/", "–", ";", "N2RA/", "–", ",", "Notch1", "Arg1974Ala", "Notch2", "Arg1934Ala", "hemizygous", ";", "P", ",", "postnatal", "day", ";", "WT", ",", "wild", "-", "type", "." ]
[ 8, 13, 0, 8, 13, 12, 13, 8, 15, 8, 8, 13, 12, 13, 13, 12, 13, 13, 12, 12, 12, 8, 8, 13, 8, 13, 0, 8, 13, 12, 13, 0, 13, 8, 13 ]
[ 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 0, 1, 0, 0, 1, 0, 0, 3, 4, 3, 4, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0 ]
169
[ "IFN", ",", "interferon", ";", "ISG", ",", "IFN", "-", "IFN", "stimulated", "gene", ";", "n.s", ".", ",", "not", "significant", ";", "RT", ",", "quantitative", "reverse", "transcription", "PCR", ";", "-qPCRrVSV", ",", "recombinant", "GFP", "-", "expressing", "vesicular", "stomatitis", "virus", ";", "SEM", ",", "standard", "error", "of", "the", "mean", ";", "siRNA", ",", "small", "interfering", "RNA", "." ]
[ 12, 13, 8, 13, 12, 13, 12, 13, 12, 16, 8, 13, 8, 13, 13, 10, 0, 13, 12, 13, 0, 0, 8, 8, 13, 12, 13, 0, 8, 13, 16, 0, 8, 8, 13, 12, 13, 0, 8, 1, 6, 8, 13, 8, 13, 0, 16, 8, 13 ]
[ 1, 0, 3, 0, 1, 0, 3, 4, 1, 4, 4, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
170
[ "The", "global", "prevalence", "of", "type", "2", "diabetes", "mellitus", "(", "T2DM", ")", "has", "been", "estimated", "to", "be", "171", "million", "cases", ",", "and", "it", "is", "projected", "to", "reach", "double", "this", "estimate", "or", "more", "by", "2030", "[", "1", "]", "." ]
[ 6, 0, 8, 1, 8, 9, 8, 8, 13, 12, 13, 3, 3, 16, 10, 3, 9, 9, 8, 13, 5, 11, 3, 16, 10, 16, 6, 6, 8, 5, 0, 1, 9, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
171
[ "Other", "biomarkers", "or", "severity", "scores", "with", "the", "gradual", "decreasing", "area", "under", "curve", "included", "delta", "sequential", "organ", "failure", "assessment", "(", "dSOFA", ")", "score", "(", "dashed", "green", "line", ")", ",", "serum", "CRP", "(", "dashed", "red", "line", ")", ",", "infection", "probability", "score", "(", "IPS", ")", "(", "dashed", "-", "double", "dot", "orange", "line", ")", ",", "multiple", "organ", "dysfunction", "scores", "(", "MODS", ")", "(", "dashed", "grass", "green", "line", ")", ",", "quick", "sequential", "organ", "failure", "assessment", "(", "qSOFA", ")", "(", "dashed", "blue", "line", ")", ",", "logistic", "organ", "dysfunction", "score", "(", "LODS", ")", "(", "dashed", "-", "dot", "pink", "line", ")", ",", "and", "acute", "physiology", "and", "chronic", "health", "evaluation", "II", "(", "APACHEII", ")", "(", "solid", "purple", "line", ")", "." ]
[ 0, 8, 5, 8, 8, 1, 6, 2, 16, 8, 1, 8, 16, 8, 0, 8, 8, 8, 13, 12, 13, 8, 13, 0, 0, 8, 13, 13, 8, 12, 13, 0, 0, 8, 13, 13, 8, 8, 8, 13, 12, 13, 13, 0, 13, 0, 8, 0, 8, 13, 13, 0, 8, 8, 8, 13, 12, 13, 13, 0, 8, 0, 8, 13, 13, 0, 0, 8, 8, 8, 13, 12, 13, 13, 0, 0, 8, 13, 13, 0, 8, 8, 8, 13, 12, 13, 13, 0, 13, 8, 0, 8, 13, 13, 5, 0, 8, 5, 0, 8, 8, 12, 13, 12, 13, 13, 0, 0, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0 ]
172
[ "SFA", "=", "saturated", "fatty", "acid", ";", "MUFA", "=", "monounsaturated", "fatty", "acid", ";", "PUFA", "=", "polyunsatutaed", "fatty", "acid", ";", "EPA", "=", "eicosapentaenoic", "acid", ";", "DHA", "=", "docosahexaenoic", "acid", ";", "IA", "=", "Index", "of", "Atherogenicity", ";", "IT", "=", "Index", "of", "Thrombogenicity", ";", "h", "=", "Hypocholesterolemic", "/", "hypercholesterolemic", "ratio", "." ]
[ 12, 13, 0, 0, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 8, 8, 13, 12, 13, 8, 8, 13, 12, 13, 8, 1, 8, 13, 12, 13, 8, 1, 8, 13, 12, 13, 0, 15, 0, 8, 13 ]
[ 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0, 1, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 0 ]
173
[ "The", "gene", "exome", "analysis", "showed", "340", "single", "nucleotide", "polymorphisms", "(", "SNPs", ")", "that", "caused", "amino", "acid", "changes", "for", "which", "the", "patient", "was", "homozygous", "and", "both", "parents", "were", "heterozygous", "." ]
[ 6, 8, 8, 8, 16, 9, 0, 8, 8, 13, 12, 13, 11, 16, 8, 8, 8, 1, 11, 6, 8, 3, 0, 5, 6, 8, 3, 0, 13 ]
[ 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
174
[ "The", "Hebrew", "version", "of", "the", "following", "questionnaires", "were", "administered", ":", "Beck", "Depression", "Inventory", "(", "BDI", ")", "(", "30", ")", ",", "Conners", "’", "Adult", "ADHD", "Rating", "Scales", "(", "CAARS", ")", "[", "36", "]", ",", "Revised", "Self", "-", "Monitoring", "Scale", "(", "RSMS", ")", "and", "the", "Concern", "for", "Appropriateness", "Scale", "(", "CAS", ")", "[", "37", "]", "." ]
[ 6, 0, 8, 1, 6, 0, 8, 3, 16, 13, 12, 12, 12, 13, 12, 13, 13, 9, 13, 13, 12, 13, 12, 12, 12, 8, 13, 12, 13, 13, 9, 13, 13, 0, 12, 13, 12, 12, 13, 12, 13, 5, 6, 12, 1, 12, 12, 13, 12, 13, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0 ]
175
[ "While", "rods", ",", "cones", ",", "and", "intrinsically", "photosensitive", "melanopsin", "-", "containing", "ganglion", "cells", "(", "ipRGCs", ")", "all", "drive", "light", "entrainment", "of", "the", "master", "circadian", "pacemaker", "of", "the", "suprachiasmatic", "nucleus", ",", "recent", "studies", "have", "proposed", "that", "entrainment", "of", "the", "mouse", "retinal", "clock", "is", "exclusively", "mediated", "by", "a", "UV", "-", "sensitive", "photopigment", ",", "neuropsin", "(", "OPN5", ")", "." ]
[ 14, 8, 13, 8, 13, 5, 2, 0, 8, 13, 16, 8, 8, 13, 12, 13, 11, 16, 8, 8, 1, 6, 8, 0, 8, 1, 6, 0, 8, 13, 0, 8, 3, 16, 14, 8, 1, 6, 8, 0, 8, 3, 2, 16, 1, 6, 8, 13, 0, 8, 13, 8, 13, 12, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 1, 0, 0 ]
176
[ "The", "number", "of", "TCRαβ+CD8αα+", "IELs", "was", "reduced", "in", "Rbpj−/−", "mice", "(", "Fig", "1C", ")", ".", "The", "number", "of", "TCRαβ+CD8αα+", "T", "cells", "in", "the", "lamina", "propria", "was", "not", "decreased", "in", "Rbpj−/−", "mice", "compared", "with", "control", "mice", "(", "Fig", "1D", ")", ".", "Although", "the", "number", "of", "TCRαβ+CD8αα+", "IELs", "was", "reduced", "in", "Rbpj−/−", "mice", ",", "the", "Rbpj−/−", "and", "Rbpj+/+", "mice", "showed", "comparable", "body", "weight", "loss", "after", "induction", "of", "colitis", "by", "dextran", "sodium", "sulfate", "(", "DSS", ")", "or", "2,4,6", "-", "Trinitrobenzene", "sulfonic", "acid", "(", "TNBS", ")", "(", "S2", "Fig", ")", "." ]
[ 6, 8, 1, 8, 12, 3, 16, 1, 12, 8, 13, 12, 9, 13, 13, 6, 8, 1, 8, 8, 8, 1, 6, 8, 8, 3, 10, 16, 1, 12, 8, 16, 1, 8, 8, 13, 12, 9, 13, 13, 14, 6, 8, 1, 8, 12, 3, 16, 1, 12, 8, 13, 6, 12, 5, 12, 8, 16, 0, 8, 8, 8, 1, 8, 1, 8, 1, 8, 8, 8, 13, 12, 13, 5, 9, 13, 8, 8, 8, 13, 12, 13, 13, 12, 12, 13, 13 ]
[ 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
177
[ "Our", "gene", "expression", "data", "were", "downloaded", "from", "three", "publicly", "available", "microarray", "gene", "expression", "datasets", "(", "Gene", "Expression", "Omnibus", "[", "GEO", "]", ":", "GSE48350", ",", "GSE5281", ",", "and", "GSE84422", ")", "." ]
[ 11, 8, 8, 8, 3, 16, 1, 9, 2, 0, 8, 8, 8, 8, 13, 12, 12, 12, 13, 12, 13, 13, 12, 13, 8, 13, 5, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
178
[ "Furthermore", ",", "they", "provide", "evidence", "suggesting", "that", "proliferating", "cell", "nuclear", "antigen", "(", "PCNA", ")", ",", "a", "protein", "found", "at", "sites", "of", "replication", ",", "is", "the", "relevant", "target", "of", "these", "chains", "in", "human", "cells", "." ]
[ 2, 13, 11, 16, 8, 16, 14, 16, 8, 0, 8, 13, 12, 13, 13, 6, 8, 16, 1, 8, 1, 8, 13, 3, 6, 0, 8, 1, 6, 8, 1, 0, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
179
[ "Untreated", "or", "lipopolysaccharide", "(", "LPS)-treatedBMDCs", "were", "loaded", "with", "OVA257", "-", "264", "peptides", ",", "and", "the", "surface", "presentation", "of", "H2", "/", "OVA257", "-", "264", "complexes", "were", "assessed", "by", "flow", "cytometry", "." ]
[ 0, 5, 8, 13, 12, 3, 16, 1, 8, 13, 9, 8, 13, 5, 6, 8, 8, 1, 12, 15, 8, 13, 9, 8, 3, 16, 1, 8, 8, 13 ]
[ 0, 0, 3, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
180
[ "The", "K220", "acetylation", "of", "the", "recombinant", "PGK1", "was", "confirmed", "by", "immunoblotting", "with", "the", "site", "-", "specific", "α", "-", "acPGK1(K220", ")", "antibody", "(", "Fig", "1E", ")", ".", "Consistent", "with", "the", "structural", "prediction", ",", "the", "recombinant", "PGK1K220ac", "protein", "was", "catalytically", "inactive", "when", "compared", "to", "recombinant", "wild", "-", "type", "PGK1", ".", "Importantly", ",", "isothermal", "titration", "calorimetry", "(", "ITC", ")", "analysis", "demonstrated", "that", "the", "recombinant", "PGK1K220ac", "protein", "was", "defective", "in", "binding", "with", "ADP", "(", "Fig", "1F", ")", ".", "These", "results", "provide", "direct", "and", "unequivocal", "biochemical", "evidence", "to", "support", "a", "model", "that", "K220", "acetylation", "in", "PGK1", "inhibits", "its", "enzymatic", "activity", "by", "blocking", "the", "substrate", "ADP", "binding", "." ]
[ 6, 12, 8, 1, 6, 0, 12, 3, 16, 1, 16, 1, 6, 8, 13, 0, 13, 13, 8, 13, 8, 13, 8, 9, 13, 13, 0, 1, 6, 0, 8, 13, 6, 0, 12, 8, 3, 2, 0, 14, 16, 10, 0, 0, 13, 8, 12, 13, 2, 13, 0, 8, 8, 13, 12, 13, 8, 16, 14, 6, 0, 12, 8, 3, 0, 1, 16, 1, 12, 13, 8, 9, 13, 13, 6, 8, 16, 0, 5, 0, 0, 8, 10, 16, 6, 8, 14, 12, 8, 1, 12, 16, 11, 0, 8, 1, 16, 6, 8, 12, 16, 13 ]
[ 0, 1, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
181
[ "Standard", "deviation", "(", "SD", ")", ",", "Baby", "Behavior", "Questionnaire", "(", "BBQ", ")", "." ]
[ 0, 8, 13, 8, 13, 13, 12, 12, 12, 13, 12, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0 ]
182
[ "The", "eukaryotic", "Zn-1", "binding", "domain", "that", "is", "not", "conserved", "in", "archaeal", "PolD", "is", "colored", "in", "gray", ".", "(", "B", ")", "Schematic", "representation", "of", "the", "DP1", "–", "DP2", "interface", "of", "PolD", "and", "the", "A", "-", "subunit", "/", "B", "-", "subunit", "interface", "of", "eukaryotic", "DNAPs", "highlighting", "the", "differences", "between", "both", "structures", ".", "cryo-EM", ",", "cryo", "–", "electron", "microscopy", ";", "CTD", ",", "C", "-", "terminal", "domain", ";", "DNAP", ",", "DNA", "polymerase", ";", "EXO", ",", "exonuclease", "active", "site", ";", "H.sa", ",", "H.", "sapiens", ";", "OB", ",", "oligonucleotide", "binding", ";", "PDB", ",", "Protein", "Data", "Bank", ";", "PDE", ",", "phosphodiesterase", "domain", ";", "ssDNA", ",", "single", "-", "stranded", "DNA", "." ]
[ 6, 0, 8, 16, 8, 11, 3, 10, 16, 1, 0, 12, 3, 16, 1, 8, 13, 13, 8, 13, 0, 8, 1, 6, 8, 13, 8, 8, 1, 12, 5, 6, 8, 13, 8, 15, 8, 13, 8, 8, 1, 0, 12, 16, 6, 8, 1, 6, 8, 13, 12, 13, 0, 13, 8, 8, 13, 12, 13, 8, 13, 0, 8, 13, 12, 13, 8, 8, 13, 12, 13, 8, 0, 8, 13, 12, 13, 8, 8, 13, 12, 13, 8, 16, 13, 12, 13, 12, 12, 12, 13, 12, 13, 8, 8, 13, 12, 13, 0, 13, 0, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 4, 0 ]
183
[ "Recently", ",", "our", "group", "has", "successfully", "employed", "a", "full", "-", "ensemble", "hybrid", "method", "that", "combines", "Langevin", "dynamics", "(", "LD", ")", "simulations", "and", "small", "-", "angle", "X", "-", "ray", "scattering", "(", "SAXS", ")", "to", "generate", "experimentally", "validated", ",", "high", "-", "resolution", "structural", "models", "of", "several", "proteins", "with", "high", "conformational", "flexibility", "[", "24–26", "]", "." ]
[ 2, 13, 11, 8, 3, 2, 16, 6, 0, 13, 8, 8, 8, 11, 16, 12, 8, 13, 12, 13, 8, 5, 0, 13, 8, 8, 13, 8, 8, 13, 12, 13, 10, 16, 2, 16, 13, 0, 13, 8, 0, 8, 1, 0, 8, 1, 0, 0, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
184
[ "The", "available", "long", "-", "term", "models", "for", "people", "with", "reduced", "kidney", "function", ",", "however", ",", "are", "either", "derived", "from", "a", "range", "of", "literature", "sources", "with", "limited", "ability", "to", "assess", "variation", "of", "effects", "across", "people", "at", "different", "disease", "risks", "[", "9–13", "]", "or", "consider", "only", "populations", "with", "moderate", "to", "advanced", "CKD", "[", "5", "]", ",", "whereas", "the", "vast", "majority", "of", "patients", "seen", "in", "primary", "care", "have", "only", "mildly", "reduced", "kidney", "function", "(", "estimated", "glomerular", "filtration", "rate", "[", "eGFR", "]", "of", "60", "to", "89", "mL", "/", "min/1.73", "m2", "[", "14", "]", ")", "." ]
[ 6, 0, 0, 13, 8, 8, 1, 8, 1, 16, 8, 8, 13, 2, 13, 3, 5, 16, 1, 6, 8, 1, 8, 8, 1, 0, 8, 10, 16, 8, 1, 8, 1, 8, 1, 0, 8, 8, 17, 17, 13, 5, 16, 2, 8, 1, 0, 10, 0, 12, 17, 17, 13, 13, 14, 6, 0, 8, 1, 8, 16, 1, 0, 8, 16, 2, 2, 16, 8, 8, 13, 16, 0, 8, 8, 17, 12, 13, 1, 9, 10, 9, 8, 15, 9, 8, 17, 9, 13, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
185
[ "A", "data", "review", "committee", "(", "DRC", ")", "was", "set", ",", "involving", "five", "independent", "members", "(", "two", "oncologists", ",", "one", "pharmacovigilance", "specialist", "(", "chair", ")", ",", "one", "statistician", ",", "one", "clinical", "pharmacologist", ")", ",", "as", "well", "as", "the", "lead", "principal", "investigator", "." ]
[ 6, 8, 8, 8, 13, 12, 13, 3, 16, 13, 16, 9, 0, 8, 13, 9, 8, 13, 9, 8, 8, 13, 8, 13, 13, 9, 8, 13, 9, 0, 8, 13, 13, 1, 2, 1, 6, 0, 0, 8, 13 ]
[ 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
186
[ "Mosquitoes", "were", "collected", "via", "two", "methods", "in", "each", "of", "the", "selected", "communities", "where", "malaria", "cases", "were", "registered", ":", "protective", "human", "-", "baited", "capture", "(", "PHBC", ")", ",", "which", "consists", "of", "exposing", "only", "one", "limb", "and", "capturing", "the", "mosquito", "upon", "landing", "before", "the", "bite", "begins", "[", "24", "]", ";", "and", "CDC", "light", "traps", "(", "LTs", ")", "." ]
[ 8, 3, 16, 1, 9, 8, 1, 11, 1, 6, 16, 8, 14, 8, 8, 3, 16, 13, 0, 0, 13, 0, 8, 13, 12, 13, 13, 11, 16, 1, 16, 2, 9, 8, 5, 16, 6, 8, 14, 8, 14, 6, 8, 16, 13, 9, 13, 13, 5, 12, 0, 8, 13, 8, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]
187
[ "(", "A", ")", "A", "selected", "region", "of", "the", "2D", "[", "1H-15N]–heteronuclear", "single", "quantum", "coherence", "(", "HSQC", ")", "experiment", "of", "15N", "-", "labeled", "α-syn", "before", "(", "blue", ")", "and", "after", "(", "red", ")", "addition", "of", "CyP40", "(", "molar", "ratio", "1:15", ")", "." ]
[ 13, 6, 13, 6, 16, 8, 1, 6, 8, 17, 0, 0, 8, 8, 13, 12, 13, 8, 1, 9, 8, 16, 12, 1, 13, 0, 13, 5, 1, 13, 0, 13, 8, 1, 12, 13, 8, 8, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0 ]
188
[ "CRISPRi", ",", "clustered", "regularly", "interspaced", "short", "palindromic", "repeat", "interference", ";", "ESC", ",", "embryonic", "stem", "cell", ";", "GFP", ",", "green", "fluorescent", "protein", ";", "IP", ",", "immunoprecipitation", ";", "MERVL", ",", "murine", "endogenous", "retrovirus", "-", "L", ";", "MS", ",", "mass", "spectrometry", ";", "NC", ",", "negative", "control", ";", "Pias4", ",", "protein", "inhibitor", "of", "activated", "STAT", "4", ";", "siRNA", ",", "small", "interfering", "RNA", ";", "Sumo2", ",", "small", "ubiquitin", "-", "like", "modifier", ";", "tdTomato", ",", "tandem", "dimeric", "Tomato", ";", "Zscan4", ",", "zinc", "finger", "and", "SCAN", "domain", "containing", "4", "." ]
[ 12, 13, 16, 2, 16, 0, 0, 8, 8, 13, 12, 13, 0, 8, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 8, 13, 12, 13, 0, 0, 8, 13, 8, 13, 12, 13, 8, 8, 13, 12, 13, 0, 8, 13, 12, 13, 8, 8, 1, 16, 12, 9, 13, 12, 13, 0, 16, 8, 13, 12, 13, 0, 8, 13, 0, 8, 13, 12, 13, 0, 0, 12, 13, 12, 13, 8, 8, 5, 8, 8, 16, 9, 13 ]
[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 0 ]
189
[ "Using", "a", "transgenic", "line", ",", "Tg(hsp70l", ":", "dnXla", ".", "Rbpj", "-", "MYC)vu21", ",", "in", "which", "a", "dominant", "negative", "form", "of", "the", "Notch", "effector", "recombination", "signal", "binding", "protein", "for", "immunoglobulin", "kappa", "J", "region", "(", "Rbpj", ")", "is", "overexpressed", "upon", "heat", "shock", ",", "we", "found", "that", "higher", "numbers", "of", "pineal", "cells", "express", "the", "pan", "-", "PhR", "marker", "anaat2", ":", "GFP", "[", "24", "]", "at", "26", ",", "36", ",", "and", "42", "hpf", "(", "but", "not", "at", "48", "hpf", ")", "relative", "to", "control", "siblings", "when", "heat", "shock", "was", "performed", "at", "14", "hpf", "(", "Fig", "3A", ",", "3B", "and", "3", "G", ")", ",", "suggesting", "that", "PhR", "production", "is", "accelerated", "upon", "reduction", "of", "Notch", "activity", ";", "this", "relatively", "late", "heat", "shock", "elicits", "only", "a", "limited", "effect", "on", "the", "PN", "population", "(", "S3A", "Fig", ")", "compared", "to", "situations", "in", "which", "Notch", "signaling", "has", "been", "impaired", "from", "earlier", "stages", "[", "24", "]", "." ]
[ 16, 6, 0, 8, 13, 12, 8, 8, 13, 12, 0, 12, 13, 1, 11, 6, 0, 0, 8, 1, 6, 12, 8, 8, 8, 16, 8, 1, 8, 8, 8, 8, 13, 12, 13, 3, 16, 14, 8, 8, 13, 11, 16, 14, 0, 8, 1, 0, 8, 16, 6, 0, 0, 12, 8, 8, 8, 12, 13, 9, 13, 1, 9, 13, 9, 13, 5, 9, 12, 13, 5, 10, 1, 9, 12, 13, 0, 1, 8, 8, 14, 8, 8, 3, 16, 1, 9, 12, 13, 12, 9, 13, 9, 5, 9, 8, 13, 13, 16, 14, 12, 8, 3, 16, 14, 8, 1, 12, 8, 13, 6, 2, 0, 8, 8, 16, 2, 6, 0, 8, 1, 6, 12, 8, 13, 12, 12, 13, 16, 1, 8, 1, 11, 12, 8, 3, 3, 16, 1, 0, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
190
[ "This", "is", "consistent", "with", "our", "results", ",", "since", "we", "have", "found", "in", "the", "present", "work", "two", "of", "the", "key", "glycolytic", "enzymes", ",", "ATP", "-", "dependent", "6", "-", "phosphofructokinase", "(", "PFKP", ")", "and", "gamma", "-", "enolase", "(", "ENO2", ")", ",", "as", "up", "-", "regulated", "in", "HGPS", "cell", "lines", "." ]
[ 11, 3, 0, 1, 11, 8, 13, 14, 11, 3, 16, 1, 6, 0, 8, 9, 1, 6, 0, 0, 8, 13, 8, 13, 0, 9, 13, 8, 13, 12, 13, 5, 8, 13, 8, 13, 12, 13, 13, 14, 2, 13, 16, 1, 12, 8, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0 ]
191
[ "With", "the", "readily", "accessible", "human", "genome", "sequence", ",", "mapping", "studies", "of", "retroviral", "integration", "sites", "in", "cell", "lines", "have", "uncovered", "nonrandom", "integration", "patterns", ",", "when", "studied", "using", "wild", "-", "type", "HIV", ",", "HIV", "-", "derived", ",", "or", "murine", "leukemia", "virus", "(", "MLV)-derived", "vectors", "(", "Elleder", "et", "al", ".", "2002", ";", "Schroder", "et", "al", ".", "2002", ";", "Laufs", "et", "al", ".", "2003", ";", "Wu", "et", "al", ".", "2003", ";", "Mitchell", "et", "al", ".", "2004", ")", "." ]
[ 1, 6, 2, 0, 0, 8, 8, 13, 8, 8, 1, 0, 8, 8, 1, 8, 8, 3, 16, 0, 8, 8, 13, 14, 16, 16, 0, 13, 8, 12, 13, 12, 13, 16, 13, 5, 8, 8, 8, 13, 12, 8, 13, 12, 8, 8, 13, 9, 13, 12, 8, 8, 13, 9, 13, 12, 8, 8, 13, 9, 13, 12, 8, 8, 13, 9, 13, 12, 8, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
192
[ "BMI", ",", "body", "mass", "index", ";", "DHEAS", ",", "dehydroepiandrosterone", "sulfate", ";", "FSH", ",", "follicle", "-", "stimulating", "hormone", ";", "Glu0", ",", "fasting", "glucose", ";", "Ins0", ",", "fasting", "insulin", ";", "LH", ",", "luteinizing", "hormone", ";", "PC", ",", "principal", "component", ";", "PCA", ",", "principal", "component", "analysis", ";", "PCOS", ",", "polycystic", "ovary", "syndrome", ";", "SHBG", ",", "sex", "hormone", "binding", "globulin", ";", "T", ",", "testosterone", "." ]
[ 12, 13, 8, 8, 8, 13, 12, 13, 8, 8, 13, 12, 13, 8, 13, 16, 8, 13, 12, 13, 16, 8, 13, 12, 13, 16, 8, 13, 12, 13, 16, 8, 13, 12, 13, 0, 8, 13, 12, 13, 0, 8, 8, 13, 12, 13, 0, 0, 8, 13, 12, 13, 8, 8, 16, 8, 13, 8, 13, 8, 13 ]
[ 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0 ]
193
[ "One", "clue", "suggesting", "the", "possibility", "that", "T", "-", "cell", "c", "-", "Fos", "may", "be", "involved", "comes", "from", "bone", "marrow", "-", "derived", "macrophages", ",", "in", "which", "receptor", "activator", "of", "nuclear", "factor", "κB", "ligand", "(", "RANKL)-induced", "osteoclast", "differentiation", "was", "impaired", "in", "c", "-", "fos-/-", "cells", "because", "of", "lack", "of", "NFAT2", "expression", "[", "29", "]", "." ]
[ 9, 8, 16, 6, 8, 14, 8, 8, 8, 8, 8, 12, 3, 3, 16, 16, 1, 8, 8, 8, 16, 8, 13, 1, 11, 8, 8, 1, 0, 8, 8, 8, 13, 12, 8, 8, 3, 16, 1, 8, 8, 8, 8, 14, 1, 8, 1, 12, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
194
[ "AP", ",", "action", "potential", ";", "RP", ",", "receptor", "potential", "." ]
[ 12, 13, 8, 8, 13, 12, 13, 8, 8, 13 ]
[ 1, 0, 3, 4, 0, 1, 0, 3, 4, 0 ]
195
[ "A", "T1", "-", "weighted", ",", "magnetization", "-", "prepared", "rapid", "acquisition", "with", "gradient", "echo", "(", "MPRAGE", ")", "was", "collected", "and", "used", "for", "coregistration", "with", "the", "functional", "images", "." ]
[ 6, 8, 13, 16, 13, 8, 13, 16, 0, 8, 1, 8, 8, 13, 12, 13, 3, 16, 5, 16, 1, 8, 1, 6, 0, 8, 13 ]
[ 0, 0, 0, 0, 0, 3, 4, 4, 4, 4, 4, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
196
[ "RNA-seq", ",", "RNA", "sequencing" ]
[ 12, 13, 8, 8 ]
[ 1, 0, 3, 4 ]
197
[ "Bak", ",", "BCL2", "Antagonist", "/", "Killer", ";", "Bax", ",", "BCL2", "-", "Associated", "X", ";", "BCL2", ",", "B", "-", "cell", "lymphoma", "2", ";", "BrdU", ",", "Bromodeoxyuridine", ";", "C", ",", "MAF", "BZIP", "Transcription", "Factor", ";", "-mafFoxe3", ",", "Forkhead", "Box", "E3", ";", "KO", ",", "knockout", ";", "N.S.", ",", "not", "significant", ";", "Pten", ",", "phosphatase", "and", "tensin", "homolog", ";", "p85;Bax", "/", "Bak", "CKO", ",", "Le", "-", "Cre;p85αf", "/", "f;p85βKO", "/", "KOBaxflox", "/", "flox;BakKO", "/", "KO", ";", "p85", ",", "Le", "-", "Cre;p85αf", "/", "f;p85βKO", "/", "KO", "CKOKO", ";", "p85;Pten", ",", "Le", "-", "Cre;p85αf", "/", "f;p85βKO", "/", "KO;Ptenf", "KO;Ptenf", "/", "f." ]
[ 12, 13, 12, 8, 15, 12, 13, 12, 13, 12, 8, 16, 12, 13, 12, 13, 8, 8, 8, 8, 9, 13, 12, 13, 8, 13, 12, 13, 12, 12, 12, 12, 13, 12, 13, 12, 12, 12, 13, 12, 13, 8, 13, 12, 13, 10, 0, 13, 12, 13, 8, 5, 8, 8, 13, 12, 15, 12, 12, 13, 12, 8, 8, 15, 17, 15, 8, 15, 8, 15, 12, 13, 12, 13, 12, 8, 8, 15, 17, 15, 12, 12, 13, 12, 13, 12, 8, 8, 15, 17, 15, 8, 12, 15, 8 ]
[ 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 0, 0, 0, 0, 0, 0, 1, 0, 3, 4, 4, 4, 0, 1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 1, 0, 1, 0, 3, 4, 4, 4, 4, 4, 4, 1, 0, 0 ]
198
[ "The", "phosphate", "-", "containing", "cofactors", "depicted", "are", "as", "follows", ":", "ATP", ",", "adenosine-5ʹ-triphosphate", ";", "AMP", ",", "adenosine", "monophosphate", ",", "and", "APR", ",", "adenosine-5", "-", "diphosphoribose", ";", "FAD", ",", "flavin", "adenine", "dinucleotide", ";", "and", "NAD", ",", "nicotinamide", "adenine", "dinucleotide", ";", "the", "non", "-", "phosphate", "-", "containing", "cofactors", "are", "as", "follows", ":", "SAM", ",", "S", "-", "adenosylmethionine", ",", "and", "dc", "-", "SAM", ",", "Adenosylmethioninamine", "." ]
[ 6, 8, 13, 16, 8, 16, 3, 14, 16, 13, 12, 13, 8, 13, 12, 13, 8, 8, 13, 5, 12, 13, 8, 13, 8, 13, 12, 13, 8, 8, 8, 13, 5, 12, 13, 8, 8, 8, 13, 6, 0, 13, 8, 13, 16, 8, 3, 14, 16, 13, 12, 13, 8, 13, 8, 13, 5, 8, 13, 12, 13, 8, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 3, 0, 1, 0, 3, 4, 0, 0, 1, 0, 3, 4, 4, 0, 1, 0, 3, 4, 4, 0, 0, 1, 0, 3, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0 ]
199
[ "Management", "of", "these", "critically", "ill", "patients", "hinges", "on", "the", "early", "identification", "of", "secondary", "injuries", "to", "the", "brain", "and", "typically", "involves", "monitoring", "of", "intracranial", "pressure", "(", "ICP", ")", "and", "cerebral", "perfusion", "pressure", "(", "CPP", ")", ".", "With", "increased", "sophistication", "of", "neuro", "-", "monitoring", "techniques", ",", "there", "is", "now", "the", "opportunity", "to", "interrogate", "cerebral", "homeostatic", "mechanisms", "that", "may", "represent", "hitherto", "underrecognized", "pathophysiological", "pathways", "[", "3", "]", "." ]
[ 8, 1, 6, 2, 0, 8, 16, 1, 6, 0, 8, 1, 0, 8, 10, 6, 8, 5, 2, 16, 8, 1, 0, 8, 13, 12, 13, 5, 0, 8, 8, 13, 12, 13, 13, 1, 16, 8, 1, 8, 8, 8, 8, 13, 11, 16, 2, 6, 8, 10, 16, 0, 0, 8, 11, 3, 16, 2, 16, 0, 8, 13, 9, 13, 13 ]
[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 1, 0, 0, 3, 4, 4, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]